This book constitutes the proceedings of the 20th International Conference of the International Graphonomics Society, IGS 2021/2022. Originally planned to be celebrated in September 2021, due to the COVID-19 pandemic it was held in June 2022.The 36 full and 3 short papers presented at the conference were carefully reviewed and selected from 41 submissions and reviewed by a committee of 67 reviewers.Out of the 41 conferences, 26 papers were selected to be published in this proceedings.The program was comprised of 6 oral sessions on the following topics: historical documents, forensic handwriting examinations, handwriting learning and development, and motor control.One additional poster session included papers on all previous topics, and three special sessions included papers on neurodegenerative disorders.