Nattokinase is a potent fibrinolytic enzyme extract that has been used in Japan for over 1000 years and may help support and maintain the health of the heart and support normal blood pressure levels. Nattokinase is an enzyme derived from 'natto', a traditional fermented soy food popular in Japan. During the natto production process B. subtilis natto, a friendly bacteria, ferments boiled soybeans, releasing nattokinase. Nattokinase and cardiovascular health Nattokinase may help to support and maintain the healthy function of the cardiovascular system and in particular support the healthy and normal dissipation of blood clots within the body. Nattokinase may also support and sustain normal and healthy blood pressure levels in humans. Prolonged Action of Nattokinase Nattokinase produces a prolonged action. Activity of Nattokinase has been determined to last from 8 to 12 hours. Doctor's Best Nattokinase contains pure nattokinase enzyme with all Vitamin K removed. 2000 FU (fibrinolytic units) is equivalent to 100mg About Doctors Best Doctors Best was founded in 1990 with the idea to create nutritional supplements rooted in research. From sourcing top-quality ingredients to working with the best manufacturers in the business, their science-based approach to nutrition sets them apart. Today, Doctors Best continue to uphold their founders belief that by trusting in science, good health will follow. They put in the work so you can thrive. Nattokinase is a potent fibrinolytic enzyme extract that has been used in Japan for over 1000 years and may help support and maintain the health of the heart and support normal blood pressure levels.