Meet some of the amazing characters and events that have shaped the world of science and medicine in History Heroes' new 500 piece jigsaw, made in the UK from 100% recycled and sustainable cardboard. History Heroes Medicine Makers takes you on a fantastically illustrated journey through 200 years of fast changing medicine and science.Piece together the puzzle and the journey from 1756, when medicine was still based on guesswork and superstition and Joseph Fry sold chocolate as a tonic from his apothecary.The packed with facts jigsaw leads you to 1953, when Crick and Watson determined the double-helix structure of DNA.Meet 14 highlighted History Heroes along the way, who shaped and changed our knowledge of medicine and health together with some of the major global, scientific and technological events that helped shape that journey too.The jigsaw timeline is in the shape of the double-helix and underscores the significance to us all of understanding the developments in medicine, science and technology, ever more so today.